Neutralization of interleukin-18 reduces severity in murine colitis and intestinal IFN-g and TNF-a production
نویسندگان
چکیده
BRITTA SIEGMUND,1 GIAMILA FANTUZZI,1 FLORIAN RIEDER,2 FABIA GAMBONI-ROBERTSON,3 HANS-ANTON LEHR,4 GUNTHER HARTMANN,2 CHARLES A. DINARELLO,1 STEFAN ENDRES,2 AND ANDREAS EIGLER2 Departments of 1Medicine and 3Surgery, University of Colorado Health Sciences Center, Denver, Colorado 80206; 2Division of Clinical Pharmacology, Medizinische Klinik Innenstadt, Klinikum of the Ludwig-Maximilians-University Munich, 80336 Munich; and 4Institute of Pathology, University of Mainz, 55131 Mainz, Germany
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The Role of Endogenous Interleukin (IL)–18, IL-12, IL-1b, and Tumor Necrosis Factor–a in the Production of Interferon-g Induced by Candida albicans in Human Whole-Blood Cultures
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